Inflammation is an organism’s defensive response to foreign bodies and injury. While this is beneficial, it can go into disarray resulting in tissue damage and the development of chronic inflammatory conditions - including arthritis, fibrosis, multiple sclerosis etc. We are interested in cells of the mononuclear phagocyte system, a group of white blood cells that play an important role in the body's immune response. The Mononuclear Phagocyte System consists of three types of cell, monocytes, macrophages and dendritic cells, each with distinct functions during both steady state and disease.